Product Name: Polyquaternium-10
Chemical Family: Cellulose Derivative, Quaternary Ammonium Compound
CAS Number: 81859-24-7
Recommended Use: Ingredient for personal care products, hair conditioners, shampoos, and skin lotions
Supplier Details: Listed manufacturer or distributor address, telephone, and emergency contact number
Synonyms: Cellulose, 2-hydroxyethyl ether, polymer with (chloromethyl)oxirane, quaternized
Classifications: Not classified as hazardous under GHS
Signal Word: None required
Hazard Statements: May cause mild eye irritation; not expected to cause skin irritation or respiratory issues under normal use
Precautionary Statements: Avoid contact with eyes; wash hands after handling
Other Hazards: Dust may cause temporary discomfort in sensitive individuals
Main Ingredient: Polyquaternium-10
Purity: Varies, typically above 90% active polymer
Non-Hazardous Components: Water, trace residuals from synthesis (such as sodium chloride, ethylene oxide derivatives)
Impurities: Minimal, tightly controlled for cosmetic grade
Eye Contact: Rinse with plenty of clean water for at least 15 minutes; seek medical advice for persistent irritation
Skin Contact: Wash with soap and water; no special treatment necessary unless irritation occurs
Inhalation: Remove to fresh air; seek assistance if breathing becomes difficult
Ingestion: Rinse mouth; drink water to dilute, do not induce vomiting
Most Important Symptoms: Slight redness or irritation possible for eyes, rare cases of mild skin dryness
Suitable Extinguishing Media: Water spray, dry chemical, CO2, foam
Specific Hazards: Does not support combustion easily; under intense heat, may release small amounts of carbon oxides or nitrogen oxides
Protective Equipment: Self-contained breathing apparatus recommended for enclosed fires
Special Procedures: Cool containers with water spray near fire
Personal Precautions: Wear protective gloves and goggles to avoid skin and eye contact
Environmental Precautions: Prevent entry to drains and surface water
Containment Methods: Use appropriate tools to collect and place spilled material into suitable container
Cleanup Procedures: Sweep up without generating excessive dust; wash area with water after collection
Disposal Guidance: Dispose collected material following local, regional, and national regulations
Handling: Avoid dust generation and direct contact with eyes; use local exhaust in poorly ventilated areas
Hygiene Practices: Wash hands thoroughly after handling
Storage Conditions: Store in cool, dry storage away from incompatible materials like strong acids or oxidizers
Container Requirements: Keep in tightly closed and labeled containers to avoid moisture accumulation and contamination
Storage Life: Stable for at least two years under recommended storage conditions
Engineering Controls: General room ventilation advisable; use local exhaust if dust is generated
Personal Protective Equipment: Protective gloves, safety goggles, dust mask if exposure to dust occurs
Occupational Exposure Limits: Not established; nuisance dust limits apply (OSHA PEL 15 mg/m³ for total dust)
Environmental Exposure Controls: Avoid release to the environment; containment preferred in case of spills
Workplace Hygiene: Prohibit eating, drinking, or smoking during handling; wash thoroughly before breaks and after work
Appearance: Off-white to pale yellow, free-flowing powder or granules
Odor: Slight or none
Solubility: Freely soluble in water; forms a viscous colloidal solution
pH (1% Solution): Typically between 6 and 8
Melting Point/Freezing Point: Not available; decomposes before melting
Boiling Point: Not applicable (polymer)
Flash Point: Not applicable; non-flammable
Vapor Pressure: Not significant
Density/Bulk Density: 0.5 – 0.7 g/cm³ for powder
Partition Coefficient: Not relevant due to polymeric structure
Chemical Stability: Stable under normal temperatures and pressure
Reactivity: Low under normal use
Incompatibilities: Strong oxidizers, strong acids
Hazardous Polymerization: Does not occur
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides under fire conditions
Acute Toxicity: No significant acute toxicity observed in standard animal tests
Skin Contact: Not considered a dermal sensitizer; slight risk of irritation at high concentrations
Eye Contact: Possible mild, transient irritation
Inhalation: Dust may cause mild discomfort
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity
Ingestion: Not expected to be harmful by ingestion in small quantities typical of accidental exposure
Notable Findings: Widely used in cosmetics, generally regarded as safe in typical concentrations
Aquatic Toxicity: Low toxicity to aquatic organisms; not expected to bioaccumulate
Persistence and Degradability: Biodegradable under environmental conditions; eventually breaks down into simple compounds
Mobility: Moderate; dissolves in water and disperses
Soil Impact: No notable adverse effects at expected concentrations
Other Effects: Best to minimize large-scale releases to maintain water quality and ecosystem health
Waste Treatment Methods: Managed as non-hazardous waste if uncontaminated
Incineration: Possible in approved waste facilities
Landfill: Acceptable under local regulations
Precautions: Follow federal, state, and local waste disposal laws for final disposition of material and contaminated packaging
Container Disposal: Rinse containers, then recycle or dispose according to accepted procedures
UN Number: Not regulated as a dangerous good
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not restricted; not classified as hazardous material
Packing Group: Not applicable
Special Precautions: Prevent packaging breakage and powder dispersion during transport
TSCA Status: Listed or exempt
US FDA: Permitted for use in cosmetics with established concentration limits
EU Status: Listed in the EU Cosmetics Ingredient Database (CosIng); allowed for personal care use
Other Regulations: Complies with international cosmetic chemical inventories
Labeling Requirements: Follows labeling guidance for non-hazardous cosmetic ingredients in shipped containers
